Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064161 | 0.87 | HCRTR1 (0.42) | PPARGPPARDPPARACHRM5CHEK2 | |
| SCHEMBL28064076 | 0.85 | PPARG (0.47) | PPARGPPARDPPARAGRM5CHRM5 | |
| SCHEMBL28064074 | 0.84 | ALDH1A1 (0.42) | TEAD1TEAD3KCNA5MAPTHRH2 | |
| SCHEMBL28064165 | 0.82 | CHEK2 (0.42) | CHEK2ACKR3HRH2HRH1 | |
| SCHEMBL28064064 | 0.82 | TEAD1 (0.41) | PPARGPPARDPPARATEAD1TEAD3 | |
| SCHEMBL28064059 | 0.82 | HRH3 (0.39) | TEAD1TEAD3ACKR3HRH2HRH1 | |
| SCHEMBL28088135 | 0.81 | PPARG (0.40) | PPARGPPARDPPARAGRM5CHRM5 | |
| SCHEMBL28064069 | 0.81 | PPARG (0.37) | PPARGPPARDPPARAGRM5CHEK2 | |
| SCHEMBL28064164 | 0.81 | SIGMAR1 (0.38) | PPARGPPARDPPARACHRM5KCNA5 | |
| SCHEMBL2225788 | 0.80 | ENPP2 (0.44) | GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |