Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064165 | 0.88 | CHEK2 (0.42) | LTA4HHRH2HRH1 | |
| SCHEMBL28064059 | 0.87 | HRH3 (0.39) | HPGDLTA4HTEAD1TEAD3HRH2 | |
| SCHEMBL28827929 | 0.86 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2L3MBTL1NPC1TP53 | |
| SCHEMBL28064161 | 0.85 | HCRTR1 (0.42) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL28064061 | 0.84 | PPARG (0.37) | TEAD1TEAD3HRH2HRH1KCNA5 | |
| SCHEMBL28064064 | 0.82 | TEAD1 (0.41) | ALDH1A1SMN1; SMN2TEAD1TEAD3KCNA5 | |
| SCHEMBL28064086 | 0.81 | LTA4H (0.39) | SMN1; SMN2LTA4HTEAD1TEAD3MAPT | |
| SCHEMBL28064164 | 0.81 | SIGMAR1 (0.38) | ALDH1A1SMN1; SMN2L3MBTL1HPGDKCNA5 | |
| SCHEMBL28827928 | 0.81 | MEN1 (0.39) | SMN1; SMN2LTA4HTEAD1TEAD3MAPT | |
| SCHEMBL2230111 | 0.80 | GRIN2B (0.48) | ALDH1A1TEAD1TEAD3HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |