Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064203 | 0.85 | PPARG (0.46) | HTR7PPARGPPARDPPARA | |
| SCHEMBL28064102 | 0.85 | KDM4E (0.41) | ALDH1A1KMT2AGAAL3MBTL1KDM4E | |
| SCHEMBL28088194 | 0.84 | PPARG (0.40) | ALDH1A1KDM4ESMN1; SMN2PPARGPPARD | |
| SCHEMBL28064060 | 0.83 | LTA4H (0.39) | ALDH1A1KMT2AHPGDMEN1PPARG | |
| SCHEMBL28064081 | 0.83 | PTGDR2 (0.40) | KMT2AHTR7MEN1PPARGHTR1A | |
| SCHEMBL28064084 | 0.83 | TEAD1 (0.47) | ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL28064071 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KMT2AGAAL3MBTL1KDM4E | |
| SCHEMBL28064164 | 0.83 | SIGMAR1 (0.38) | ALDH1A1KMT2AGAAL3MBTL1KDM4E | |
| SCHEMBL2228348 | 0.82 | HTT (0.39) | ALDH1A1KMT2AGAAL3MBTL1GPBAR1 | |
| SCHEMBL28064086 | 0.81 | LTA4H (0.39) | KMT2ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | disclosed |