Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.55 |
| ▸ | MMP1 | P03956 | 5/20 | 0.55 |
| ▸ | MMP7 | P09237 | 4/20 | 0.55 |
| ▸ | MMP12 | P39900 | 4/20 | 0.55 |
| ▸ | ACE | P12821 | 3/20 | 0.55 |
| ▸ | MMP9 | P14780 | 4/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27182979 | 0.87 | MMP13 (0.57) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL28842545 | 0.86 | MMP13 (0.56) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL2810869 | 0.83 | PSIP1 (0.44) | MMP13MMP1MMP7MMP12ACE | |
| Hydrochloric Acid SCHEMBL5124022 | 0.82 | PSIP1 (0.42) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL12645204 | 0.82 | MMP13 (0.52) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL2023655 | 0.82 | MMP13 (0.52) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL7324090 | 0.82 | MMP13 (0.71) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL9754526 | 0.81 | MMP9 (0.54) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL12933668 | 0.81 | MMP9 (0.54) | MMP13MMP1MMP7MMP12ACE | |
| SCHEMBL8997318 | 0.80 | MMP3 (0.41) | MMP13MMP1MMP7MMP12ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150556-B2 | Benzimidazolone chymase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20100240702-A1 | Benzimidazolone Chymase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240702-A1 | Benzimidazolone Chymase Inhibitors | CMA1, SERPINB1, CPA3 | MMP13 321/4885MMP1 206/4885MMP7 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.