Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.45 |
| ▸ | CA1 known ✓ | P00915 | 9/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 9/20 | 0.44 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.44 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 8/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122978 | 0.98 | RECQL (0.55) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL699887 | 0.98 | RECQL (0.55) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL124817 | 0.98 | RECQL (0.55) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL28091240 | 0.96 | RECQL (0.53) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL28448153 | 0.94 | TSHR (0.48) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL126016 | 0.92 | TSHR (0.47) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL9777699 | 0.92 | RECQL (0.57) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL10525027 | 0.92 | RECQL (0.57) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL123320 | 0.92 | TSHR (0.47) | RECQLEPHX2TSHRMAPK1GLA | |
| SCHEMBL29930427 | 0.90 | RECQL (0.55) | RECQLEPHX2TSHRMAPK1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106183520-A | Original edition of lithographic printing plate and printing process thereof | 富士胶片株式会社 | 2016-12-07 | — | — | CN | disclosed |
| CN-105838143-A | Ink set and image forming method | 富士胶片株式会社 | 2016-08-10 | — | — | CN | disclosed |