SCHEMBL28077949

SCHEMBL28077949

FC(F)(F)CSc1ccc(SCC(F)(F)F)cc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
PTPRZ1 P23471 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPK1 P28482 1/20 0.33
PTPN1 P18031 1/20 0.33
DAO P14920 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777232 0.90 MAOA (0.40) ALDH1A1TDP1DAO
SCHEMBL8030618 0.88 RAB9A (0.42) ALDH1A1KDM4ETDP1DAO
SCHEMBL3115384 0.88 SMN1; SMN2 (0.44) ALDH1A1
SCHEMBL10577476 0.88
SCHEMBL8034515 0.88 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1MAPK1
SCHEMBL8021260 0.88 MLYCD (0.41) ALDH1A1KDM4ETDP1MAPK1
SCHEMBL8669085 0.88 NR1H2 (0.44) ALDH1A1KDM4ETDP1
SCHEMBL779142 0.87 ALDH1A1 (0.52) ALDH1A1MAPK1
SCHEMBL1008705 0.83
SCHEMBL22242836 0.82 LMNA (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105722830-B Aryl thioethers derivative and aryl sulfoxid es derivative as acaricide and insecticide 拜耳作物科学股份公司 2019-06-04 CN disclosed
CN-105722830-A Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides 拜耳作物科学股份公司 2016-06-29 CN disclosed