SCHEMBL2808479

SCHEMBL2808479

O=C(O)CCCCCNC(=O)C(=O)NCCCCCC(=O)O

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.74
ADRA1A P35348 1/20 0.68
PLA2G2A P14555 2/20 0.66
EPHX2 P34913 5/20 0.65
LMNA P02545 2/20 0.60
TSHR P16473 1/20 0.60
NFKB1 P19838 1/20 0.60
PMP22 Q01453 1/20 0.60
PLA2G4A P47712 1/20 0.60
MAPK1 P28482 1/20 0.59
GPR84 Q9NQS5 1/20 0.50
FFAR1 O14842 1/20 0.50
FFAR4 Q5NUL3 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11127968 1.00 PRMT1 (0.74) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL13401859 0.89 PRMT1 (0.61) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL14919046 0.88 PRMT1 (0.64) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL15154019 0.87 ADRA1A (0.59) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL20663409 0.87 ADRA1A (0.70) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL6065930 0.85 PRMT1 (0.74) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL2804471 0.85 PRMT1 (1.00) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL29896407 0.85 PRMT1 (0.74) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL17087514 0.85 PRMT1 (0.74) PRMT1ADRA1APLA2G2AEPHX2LMNA
SCHEMBL14433699 0.85 PRMT1 (1.00) PRMT1ADRA1APLA2G2AEPHX2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
US-4384083-A POLYURETHANE, POLYESTER, POLYAMIDE APPLIED POLYMER TECHNOLOGY, INCORPORATED (US) 1983-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 PRMT1 4663/4885ADRA1A 4844/4885PLA2G2A 523/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB PRMT1 2654/4885ADRA1A 4879/4885PLA2G2A 1938/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA PRMT1 2072/4885ADRA1A 4380/4885PLA2G2A 2461/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA PRMT1 1066/4885ADRA1A 4779/4885PLA2G2A 2174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.