Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085734 | 0.88 | MTNR1A (0.46) | MTNR1AMTNR1BAPPFFAR4LMNA | |
| SCHEMBL20954703 | 0.86 | MEN1 (0.51) | MTNR1AMTNR1BALDH1A1LMNAPPARG | |
| SCHEMBL28085676 | 0.84 | CFD (0.53) | MTNR1AMTNR1BAPPFFAR4ALDH1A1 | |
| SCHEMBL5446276 | 0.81 | L3MBTL1 (0.53) | MTNR1AMTNR1BALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL20954710 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BALDH1A1SMN1; SMN2PPARA | |
| SCHEMBL20954694 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1SMN1; SMN2PPARA | |
| SCHEMBL20954700 | 0.80 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1POLBHTT | |
| SCHEMBL29284729 | 0.80 | LMNA (0.52) | ALDH1A1LMNAHTTPTGER1SMPD1 | |
| SCHEMBL28085585 | 0.80 | FFAR4 (0.49) | FFAR4LMNAPTGER1SMPD1 | |
| SCHEMBL28085590 | 0.80 | PTGER1 (0.52) | ALDH1A1SMN1; SMN2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-B | Pyrans and the different cresol derivatives of baynide fibre and metabolic syndrome or treatment of inflammatory diseases pharmaceutical composition | 格拉斯如睦株式会社 | 2018-05-04 | — | — | CN | disclosed |
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |