Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 12/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446276 | 0.85 | L3MBTL1 (0.53) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29284729 | 0.84 | LMNA (0.52) | PTGER1ALDH1A1RAB9A | |
| SCHEMBL20954700 | 0.84 | MTNR1A (0.58) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28085585 | 0.84 | FFAR4 (0.49) | PTGER1MRGPRX4NPC1PPIA | |
| SCHEMBL28085734 | 0.84 | MTNR1A (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31757763 | 0.83 | L3MBTL1 (0.56) | PTGER1ALDH1A1TP53 | |
| SCHEMBL2988197 | 0.83 | L3MBTL1 (0.56) | PTGER1ALDH1A1TP53 | |
| SCHEMBL28085676 | 0.83 | CFD (0.53) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL20954694 | 0.82 | MTNR1A (0.48) | MRGPRX4NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL28204618 | 0.82 | KEAP1 (0.45) | MRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |