Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | F11 | P03951 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085734 | 0.88 | MTNR1A (0.46) | MTNR1AMTNR1BNPC1PKMRAB9A | |
| SCHEMBL28085694 | 0.87 | CFD (0.68) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL17772660 | 0.85 | CFD (0.57) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL5446276 | 0.84 | L3MBTL1 (0.53) | MTNR1AMTNR1BNPC1RAB9AALDH1A1 | |
| SCHEMBL28085581 | 0.84 | MTNR1A (0.54) | MTNR1AMTNR1BSMPD1ALDH1A1LMNA | |
| SCHEMBL29284729 | 0.83 | LMNA (0.52) | RAB9ASMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL20954700 | 0.83 | MTNR1A (0.58) | MTNR1AMTNR1BNPC1RAB9AHDAC8 | |
| SCHEMBL28085585 | 0.83 | FFAR4 (0.49) | NPC1SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL28085590 | 0.83 | PTGER1 (0.52) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2988197 | 0.82 | L3MBTL1 (0.56) | CFDPLGPLAUF11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-B | Pyrans and the different cresol derivatives of baynide fibre and metabolic syndrome or treatment of inflammatory diseases pharmaceutical composition | 格拉斯如睦株式会社 | 2018-05-04 | — | — | CN | disclosed |
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |