Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28006547 | 0.85 | CALM1 (0.41) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL2093026 | 0.79 | ALOX5 (0.53) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL15474793 | 0.79 | LMNA (0.47) | MAOBSMN1; SMN2ALOX5LMNACYP1A2 | |
| SCHEMBL7468357 | 0.78 | AGXT (0.43) | MAOBALOX5IDO1MRGPRX4AGXT | |
| SCHEMBL4315473 | 0.78 | SLC6A4 (0.40) | MAOBENPP2ALOX5PLAULMNA | |
| SCHEMBL20577100 | 0.78 | MAOB (0.53) | MAOBGAAMAPTRAB9AALOX5 | |
| SCHEMBL7295428 | 0.78 | L3MBTL1 (0.44) | MAOBGAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10743886 | 0.78 | MAOB (0.40) | MAOBMAOAL3MBTL1ALOX5LMNA | |
| SCHEMBL5494255 | 0.76 | MGLL (0.40) | MAOB | |
| SCHEMBL2202368 | 0.75 | MAOB (0.58) | MAOBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |