Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28006547 | 0.77 | CALM1 (0.41) | CYP4F2CYP4A11BCHEMAOBMEN1 | |
| SCHEMBL1171847 | 0.77 | MGLL (0.64) | MGLLCYP4F2CYP4A11BCHEMAOB | |
| SCHEMBL28085689 | 0.76 | MAOB (0.49) | MAOB | |
| SCHEMBL10411638 | 0.75 | MTNR1A (0.50) | MEN1KMT2A | |
| SCHEMBL20577100 | 0.74 | MAOB (0.53) | THRATHRBMAOB | |
| SCHEMBL1172079 | 0.73 | LTA4H (0.66) | MGLLLTA4HEPHX2BCHEMAOB | |
| SCHEMBL1172330 | 0.73 | LTA4H (0.66) | MGLLLTA4HEPHX2BCHEMAOB | |
| SCHEMBL2093026 | 0.72 | ALOX5 (0.53) | CYP4F2CYP4A11BCHEMAOBMEN1 | |
| SCHEMBL15474793 | 0.72 | LMNA (0.47) | CYP4F2CYP4A11THRATHRBMAOB | |
| SCHEMBL9558437 | 0.72 | MGLL (0.43) | MGLLLTA4HEPHX2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453816-B1 | PHENOXY AMINE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2013-09-18 | — | — | EP | disclosed |
| CN-1596248-B | Phenoxyamine compounds and compositions for delivery of active agents | EMISPHERE TECH INC | 2012-05-09 | — | — | CN | disclosed |
| US-7297794-B2 | Phenoxy amine compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20050119502-A1 | Phenoxy amine compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-06-02 | — | — | US | disclosed |
| CN-1596248-A | Phenoxy amine compounds and compositions for delivering active agents | EMISPHERE TECH INC (US) | 2005-03-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119502-A1 | Phenoxy amine compounds and compositions for delivering active agents | PNMT, SLC5A7, PHOSPHO1 | MGLL 1122/4885CYP4F2 718/4885CYP4A11 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.