Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314526 | 0.81 | CA2 (0.39) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL16019380 | 0.81 | CA1 (0.39) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL4665197 | 0.81 | ALDH1A1 (0.41) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL29890712 | 0.78 | CA1 (0.62) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL1542687 | 0.78 | CA1 (0.62) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL14461307 | 0.77 | P2RX7 (0.36) | HSD11B1POLBKMT2AMEN1 | |
| SCHEMBL14461320 | 0.76 | GABRA1 (0.41) | PDK2HSD11B1POLBKMT2AMEN1 | |
| SCHEMBL23726465 | 0.75 | HCAR1 (0.40) | CA1CA2CA5ACA9PDK2 | |
| SCHEMBL696825 | 0.74 | ALDH1A1 (0.48) | CA1CA2CA5ACA9PDK2 | |
| SCHEMBL29406141 | 0.74 | ALDH1A1 (0.48) | CA1CA2CA5ACA9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849101-A | Novel imidazolidine-2,4-dione derivatives | 益普生制药股份有限公司 | 2016-08-10 | — | — | CN | disclosed |