Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522374 | 0.78 | ENPP2 (0.43) | ENPP2ALDH1A1HSD17B10LMNAG6PD | |
| SCHEMBL2651077 | 0.73 | G6PD (0.43) | ENPP2ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL1172197 | 0.73 | L3MBTL1 (0.46) | ENPP2ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL2877852 | 0.68 | PTGS2 (0.39) | ENPP2ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL3789997 | 0.68 | PRSS1 (0.39) | ALDH1A1TSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL2437487 | 0.67 | HTR6 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL2439100 | 0.66 | ALDH1A1 (0.55) | ENPP2ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL29858642 | 0.65 | TP53 (0.50) | LMNAG6PDIDE | |
| SCHEMBL30417125 | 0.65 | G6PD (0.37) | ENPP2ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL1172365 | 0.65 | PTGS2 (0.43) | LMNAG6PDIDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103497211-B | Indoloquinoline derivant and its preparation method and application | 中国海洋大学 | 2016-07-20 | — | — | CN | disclosed |