Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648267 | 0.88 | FDPS (0.45) | FDPSALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2809278 | 0.84 | FDPS (0.46) | FDPSALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2808779 | 0.82 | ALDH1A1 (0.52) | FDPSALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2806937 | 0.82 | ALDH1A1 (0.48) | FDPSALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL29803132 | 0.81 | TUBB1 (0.50) | FDPSALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL1766183 | 0.81 | TUBB1 (0.50) | FDPSALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL16680535 | 0.81 | FDPS (0.50) | FDPSALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL12525838 | 0.79 | FDPS (0.55) | FDPSALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL7959829 | 0.77 | ALDH1A1 (0.40) | FDPSALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL2306018 | 0.77 | TUBB1 (0.47) | ALDH1A1HPGDTUBB1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975252-B2 | Morpholine derivative | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2015-03-10 | — | — | US | disclosed |
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | REN, AGTR1, AGTR2 | FDPS 3987/4885ALDH1A1 2202/4885MAPT 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.