Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103613 | 0.81 | MGLL (0.37) | LMNAALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL28103531 | 0.78 | POLB (0.38) | ALDH1A1MAPTL3MBTL1POLBMEN1 | |
| SCHEMBL28103276 | 0.77 | KDM4E (0.39) | TP53POLBKDM4E | |
| SCHEMBL27380663 | 0.76 | ALOX5 (0.44) | MEN1KMT2A | |
| SCHEMBL27873898 | 0.76 | NOTUM (0.36) | LMNAALDH1A1MAPTTP53HPGD | |
| SCHEMBL28103270 | 0.76 | ALDH1A1 (0.34) | LMNAALDH1A1GAAMAPK1 | |
| SCHEMBL27671224 | 0.76 | ALOX5 (0.41) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27505117 | 0.75 | DDB1 (0.31) | — | |
| SCHEMBL28103547 | 0.73 | ADRB2 (0.41) | ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28103503 | 0.72 | NOTUM (0.40) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061950-A | Method for producing pyrazole compound | 住友化学株式会社 | 2016-10-26 | — | — | CN | disclosed |