SCHEMBL2811067

SCHEMBL2811067

NCC(=O)NC(Cc1c[nH]cn1)C(=O)O.[Cu]

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC15A2 Q16348 1/20 0.41
ITGB3 P05106 7/20 0.36
ITGA2B P08514 7/20 0.36
CPB2 Q96IY4 6/20 0.35
CPB1 P15086 1/20 0.35
CTSC P53634 2/20 0.33
PIN1 Q13526 1/20 0.33
P2RY14 Q15391 1/20 0.33
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954680 1.00 SLC15A2 (0.41) SLC15A2ITGB3ITGA2BCPB2CPB1
SCHEMBL1666820 0.99 SLC15A2 (0.42) SLC15A2ITGB3ITGA2BCPB2CPB1
SCHEMBL483799 0.99 SLC15A2 (0.42) SLC15A2ITGB3ITGA2BCPB2CPB1
Hydrochloric Acid SCHEMBL2199717 0.97 SLC15A2 (0.41) SLC15A2ITGB3ITGA2BCPB2CPB1
Hydrochloric Acid SCHEMBL1436163 0.97 SLC15A2 (0.41) SLC15A2ITGB3ITGA2BCPB2CPB1
SCHEMBL4588249 0.97 SLC15A2 (0.41) SLC15A2ITGB3ITGA2BCPB2CPB1
SCHEMBL29590566 0.93 SLC15A2 (0.49) SLC15A2ITGB3ITGA2BCPB2CPB1
SCHEMBL20783813 0.93 SLC15A2 (0.49) SLC15A2ITGB3ITGA2BCPB2CPB1
SCHEMBL31453803 0.93 SLC15A2 (0.49) SLC15A2ITGB3ITGA2BCPB2CPB1
SCHEMBL29888249 0.90 SLC15A2 (0.44) SLC15A2ITGB3ITGA2BCPB2CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 US disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 US disclosed
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2005-11-24 US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 US disclosed
EP-0765152-B1 STIMULATION OF HAIR GROWTH BY PEPTIDE-COPPER COMPLEXES PROCYTE CORP (US) 2001-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 SLC15A2 2091/4885ITGB3 4478/4885ITGA2B 4335/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC SLC15A2 1553/4885ITGB3 4140/4885ITGA2B 4545/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 SLC15A2 2514/4885ITGB3 3811/4885ITGA2B 4303/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 SLC15A2 3106/4885ITGB3 4719/4885ITGA2B 4785/4885
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, CTRC SLC15A2 981/4885ITGB3 3569/4885ITGA2B 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.