Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111776 | 0.91 | MAPT (0.64) | MMP13HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL28111232 | 0.89 | HTT (0.58) | MMP13HPGDALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28836629 | 0.88 | VNN1 (0.56) | MMP13HPGDMAPTKDM4EKMT2A | |
| SCHEMBL28111270 | 0.77 | CNR2 (0.60) | MAPTALDH1A1KMT2AMT-CO2MEN1 | |
| SCHEMBL28111211 | 0.77 | MT-CO2 (0.52) | MAPTMT-CO2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28111752 | 0.77 | TP53 (0.48) | MMP13HPGDALDH1A1KMT2AGLA | |
| SCHEMBL5370386 | 0.73 | MMP13 (0.62) | MMP13HPGDMAPTALDH1A1KMT2A | |
| SCHEMBL28111738 | 0.73 | SMN1; SMN2 (0.48) | MMP13HPGDMAPTALDH1A1KMT2A | |
| SCHEMBL28836205 | 0.73 | SMN1; SMN2 (0.54) | MMP13HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL5357501 | 0.73 | MT-CO2 (0.83) | HPGDALDH1A1KDM4EKMT2AMT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |