Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111733 | 0.91 | MMP13 (0.52) | MAPTLMNAKDM4EHPGDMEN1 | |
| SCHEMBL28836629 | 0.87 | VNN1 (0.56) | MAPTLMNAKDM4EHPGDMEN1 | |
| SCHEMBL28111232 | 0.81 | HTT (0.58) | HPGDKMT2AMMP13ALDH1A1NPSR1 | |
| SCHEMBL991659 | 0.78 | MAPT (0.59) | MAPTLMNAKDM4EHPGDMEN1 | |
| SCHEMBL28111270 | 0.77 | CNR2 (0.60) | MAPTLMNAMEN1KMT2ACNR2 | |
| SCHEMBL28111211 | 0.77 | MT-CO2 (0.52) | MAPTCNR2DHODHVNN1CYP1A2 | |
| SCHEMBL5226231 | 0.72 | HDAC6 (0.72) | LMNAHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL28111752 | 0.72 | TP53 (0.48) | HPGDKMT2AMMP13ALDH1A1 | |
| SCHEMBL8177097 | 0.69 | RAB9A (0.72) | MAPTHPGDMEN1KMT2ACNR1 | |
| SCHEMBL3461078 | 0.69 | HDAC6 (0.70) | LMNAMEN1KMT2ASCN2ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |