Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836205 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTPOLBRXFP1HPGD | |
| SCHEMBL27021656 | 0.73 | KMT2A (0.65) | SMN1; SMN2MAPTHPGDALDH1A1KMT2A | |
| SCHEMBL28111733 | 0.73 | MMP13 (0.52) | SMN1; SMN2CNR2MAPTHPGDMMP13 | |
| SCHEMBL5452563 | 0.72 | CNR2 (0.84) | CNR2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17661849 | 0.69 | HPGD (0.60) | SMN1; SMN2CNR2HPGDALDH1A1KMT2A | |
| SCHEMBL28111242 | 0.68 | RAB9A (0.53) | SMN1; SMN2POLBHPGDMMP13ALDH1A1 | |
| SCHEMBL27813617 | 0.68 | MAPT (0.50) | SMN1; SMN2MAPTALDH1A1CYP2C19MAPK1 | |
| SCHEMBL21644655 | 0.67 | HSP90AA1 (0.64) | SMN1; SMN2HPGDALDH1A1KMT2ACYP2C19 | |
| SCHEMBL28836629 | 0.66 | VNN1 (0.56) | SMN1; SMN2CNR2MAPTHPGDMMP13 | |
| SCHEMBL28111776 | 0.66 | MAPT (0.64) | CNR2MAPTHPGDMMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |