Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27621448 | 0.86 | MAPT (0.38) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL28255189 | 0.83 | F2 (0.34) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL27697694 | 0.82 | MEN1 (0.40) | LMNASMN1; SMN2ALDH1A1HTTMEN1 | |
| SCHEMBL28256705 | 0.81 | USP28 (0.35) | LMNASMN1; SMN2ALDH1A1HTTMEN1 | |
| SCHEMBL27656469 | 0.78 | HTR6 (0.52) | LMNASMN1; SMN2ALDH1A1HTTMEN1 | |
| SCHEMBL28840342 | 0.77 | POLB (0.42) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL27944975 | 0.76 | MAPT (0.52) | LMNASMN1; SMN2ALDH1A1HTTMEN1 | |
| SCHEMBL28001305 | 0.76 | TRPV1 (0.40) | LMNAHPGDTP53 | |
| SCHEMBL28293019 | 0.74 | LMNA (0.36) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL28794456 | 0.74 | MEN1 (0.39) | LMNASMN1; SMN2ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279071-A | Phenylpiperazine derivatives and using method thereof and purposes | 广东东阳光药业有限公司 | 2017-01-04 | — | — | CN | disclosed |