Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ACP1 | P24666 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27621448 | 0.84 | MAPT (0.38) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL28112677 | 0.83 | LMNA (0.43) | GAANPC1RAB9ARBP4ALDH1A1 | |
| SCHEMBL27697694 | 0.78 | MEN1 (0.40) | GAARBP4ALDH1A1MAPTMEN1 | |
| SCHEMBL28256705 | 0.77 | USP28 (0.35) | RBP4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27656469 | 0.74 | HTR6 (0.52) | RBP4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28840342 | 0.73 | POLB (0.42) | GAARBP4ALDH1A1MAPTMEN1 | |
| SCHEMBL28293019 | 0.73 | LMNA (0.36) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL27859336 | 0.72 | DRD2 (0.48) | GAAALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL27666678 | 0.72 | MAPT (0.50) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28761804 | 0.71 | SLC6A9 (0.45) | GAAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863986-A | The Phenylpiperazine derivatives and application thereof that difluoromethyl replaces | 广东东阳光药业有限公司 | 2018-11-23 | — | — | CN | disclosed |