Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256698 | 0.87 | NPY2R (0.41) | NPY2RTAAR1GLAKDM4EMAPT | |
| SCHEMBL28258165 | 0.87 | L3MBTL1 (0.39) | NPY2RTSHRMAPK1LMNAMEN1 | |
| SCHEMBL29707436 | 0.83 | BACE1 (0.44) | BACE1LMNAMEN1KMT2AMAPT | |
| SCHEMBL19212428 | 0.83 | BACE1 (0.44) | BACE1LMNAMEN1KMT2AMAPT | |
| SCHEMBL28256722 | 0.81 | ITGB3 (0.40) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28112677 | 0.81 | LMNA (0.43) | RBP4TSHRLMNAMEN1KMT2A | |
| SCHEMBL27621448 | 0.80 | MAPT (0.38) | NPY2RLMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL28255189 | 0.77 | F2 (0.34) | RBP4TSHRMEN1KMT2AKDM4E | |
| SCHEMBL27697694 | 0.76 | MEN1 (0.40) | RBP4TSHRLMNACYP1A2GLA | |
| SCHEMBL28256767 | 0.76 | USP28 (0.34) | USP28USP25NPY2RTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |