Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 9/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.39 |
| ▸ | CSF1R | P07333 | 5/20 | 0.39 |
| ▸ | LYN | P07948 | 5/20 | 0.39 |
| ▸ | KIT | P10721 | 5/20 | 0.39 |
| ▸ | SRC | P12931 | 5/20 | 0.39 |
| ▸ | FLT4 | P35916 | 5/20 | 0.39 |
| ▸ | FLT3 | P36888 | 5/20 | 0.39 |
| ▸ | BLK | P51451 | 5/20 | 0.39 |
| ▸ | FYN | P06241 | 4/20 | 0.39 |
| ▸ | FLT1 | P17948 | 4/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2816880 | 0.89 | CDK8 (0.41) | BLMKDRLCKCSF1RLYN | |
| SCHEMBL2814666 | 0.88 | RAF1 (0.38) | KDRNTRK1CYP1A2PDGFRB | |
| SCHEMBL2816898 | 0.86 | EPHX2 (0.38) | KDM4E | |
| SCHEMBL2814901 | 0.84 | RAB9A (0.40) | NTRK1NTRK2 | |
| SCHEMBL2819223 | 0.84 | SLC6A3 (0.35) | — | |
| SCHEMBL2816391 | 0.84 | COPS5 (0.39) | — | |
| SCHEMBL2817152 | 0.84 | EPHX2 (0.41) | IDO1 | |
| SCHEMBL2818263 | 0.82 | RAB9A (0.39) | KDM4E | |
| SCHEMBL2814559 | 0.82 | CHIT1 (0.39) | KDM4EIDO1 | |
| SCHEMBL2812262 | 0.82 | KCNMA1 (0.50) | KDRNTRK1NTRK2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249132-A1 | IMIDAZOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-09-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249132-A1 | IMIDAZOLE DERIVATIVES | SDHA, SDHB, TPD52L2 | BLM 340/4885KDR 1879/4885LCK 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.