Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tipepidine SCHEMBL13723968 | 0.82 | OPRM1 (0.35) | OPRM1OPRD1KMT2AMEN1ALDH1A1 | |
| Tipepidine SCHEMBL410090 | 0.78 | NOS3 (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| Tipepidine SCHEMBL30827547 | 0.77 | NOS3 (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| Tipepidine SCHEMBL11026418 | 0.72 | HPGDS (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| Tipepidine SCHEMBL663025 | 0.69 | KDM4E (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11319505 | 0.59 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL11352518 | 0.58 | HRH2 (0.45) | OPRM1OPRD1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11354148 | 0.58 | KMT2A (0.46) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL11311454 | 0.57 | ALDH1A1 (0.45) | OPRM1OPRD1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11356487 | 0.57 | HRH2 (0.44) | OPRM1OPRD1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |