Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tipepidine SCHEMBL28142103 | 0.82 | OPRM1 (0.34) | OPRM1OPRD1MAPK1MEN1KMT2A | |
| Tipepidine SCHEMBL410090 | 0.80 | NOS3 (0.43) | MEN1KMT2AALDH1A1TSHRHTT | |
| Tipepidine SCHEMBL30827547 | 0.79 | NOS3 (0.42) | MEN1KMT2AALDH1A1TSHRHTT | |
| Tipepidine SCHEMBL11026418 | 0.74 | HPGDS (0.43) | MEN1KMT2AALDH1A1TSHRHTT | |
| Tipepidine SCHEMBL663025 | 0.73 | KDM4E (0.41) | MAPK1MEN1KMT2AALDH1A1TSHR | |
| Piperidione SCHEMBL141847 | 0.68 | LMNA (0.43) | MEN1KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL11310471 | 0.58 | OPRM1 (0.58) | OPRM1OPRD1MAPK1MEN1KMT2A | |
| SCHEMBL11319505 | 0.57 | KMT2A (0.47) | MEN1KMT2AALDH1A1TSHRNOS3 | |
| Hydrochloric Acid SCHEMBL11354148 | 0.57 | KMT2A (0.46) | MEN1KMT2AALDH1A1TSHRNOS3 | |
| Bromomethane SCHEMBL11492297 | 0.56 | RAB9A (0.39) | KMT2AALDH1A1TSHRNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699572-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Origenis GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| EP-2699579-A1 | PYRAZOLO [4, 3-D]PYRIMIDINES USEFUL AS KINASE INHIBITORS | Origenis GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143143-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
| WO-2012143144-A1 | PYRAZOLO [4, 3-D] PYRIMIDINES USEFUL AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |