Tipepidine

Tipepidine

SCHEMBL663025

CN1CCCC(=C(c2cccs2)c2cccs2)C1.O=C(O)CC(O)(CC(=O)O)C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2

The experimentally established mechanism targets of Tipepidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.38
KDM4E B2RXH2 3/20 0.41
TSHR P16473 4/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 3/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
KMT2A Q03164 1/20 0.38
CASP1 P29466 1/20 0.37
HTT P42858 1/20 0.37
GAA P10253 1/20 0.36
SRPK1 Q96SB4 1/20 0.35
MAPK1 P28482 1/20 0.35
TP53 P04637 3/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tipepidine SCHEMBL410090 0.83 NOS3 (0.43) KDM4ETSHRALDH1A1LMNAALOX15
Tipepidine SCHEMBL30827547 0.82 NOS3 (0.42) TSHRALDH1A1LMNAALOX15MEN1
Tipepidine SCHEMBL11026418 0.82 HPGDS (0.43) KDM4ETSHRALDH1A1LMNAMAPT
Tipepidine SCHEMBL13723968 0.73 OPRM1 (0.35) KDM4ETSHRALDH1A1MAPTMEN1
Tipepidine SCHEMBL28142103 0.69 OPRM1 (0.34) TSHRALDH1A1LMNAMEN1KMT2A
Citric Acid SCHEMBL7204691 0.67 ALDH1A1 (0.58) KDM4ETSHRALDH1A1LMNAMAPT
Citric Acid SCHEMBL7204241 0.67 ALDH1A1 (0.58) KDM4ETSHRALDH1A1LMNAMAPT
Citric Acid SCHEMBL27985707 0.64 ALDH1A1 (0.42) KDM4ETSHRALDH1A1LMNAMAPT
Citric Acid SCHEMBL2724333 0.64 BRD4 (0.55) KDM4ETSHRALDH1A1LMNAMAPT
Citric Acid SCHEMBL28991395 0.63 BRD4 (0.53) KDM4ETSHRALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025009819-A1 CUTTABLE AND CONSUMABLE TAPE-TYPE OR BAR-TYPE PREPARATION ENABLING DRUG DOSE CONTROL THROUGH LENGTH 충북대학교 산학협력단 2025-01-09 WO claimed
EP-1558214-B1 MICROEMULSION CONCENTRATE FOR ORAL ADMINISTRATION OF WATER-INSOLUBLE ANTI-COLD DRUG AND METHOD FOR PREPARING SAME HANMI PHARM IND CO LTD (KR) 2012-09-12 EP claimed
US-20090169682-A1 Functional Masticatory Material, Method Of Producing The Same And Method Of Using The Same MEIJI PHARMACEUTICAL CO., LTD. (JP) 2009-07-02 US claimed
US-20060062810-A1 Microemulsion concentrate for oral administration of water-insoluble anti-cold drug and method for preparing same HANMI PHARM CO., LTD. (KR) 2006-03-23 US claimed
WO-2005094832-A1 COMPOSITIONS COMPRISING MELOXICAM BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-10-13 WO claimed
EP-1558214-A1 MICROEMULSION CONCENTRATE FOR ORAL ADMINISTRATION OF WATER-INSOLUBLE ANTI-COLD DRUG AND METHOD FOR PREPARING SAME Hanmi Pharm. Co., Ltd. (KR) 2005-08-03 EP claimed
WO-2004041249-A1 MICROEMULSION CONCENTRATE FOR ORAL ADMINISTRATION OF WATER-INSOLUBLE ANTI-COLD DRUG AND METHOD FOR PREPARING SAME HANMI PHARM. CO., LTD. (KR) 2004-05-21 WO claimed
JP-62072688-A None JP disclosed
JP-5139996-A None JP disclosed
EP-4692178-A1 CELLULOSE POWDER AND MOLDED BODY Asahi Kasei Kabushiki Kaisha (JP) 2026-02-11 EP disclosed
US-12427113-B2 Cellulose composition, tablet, and orally disintegrating tablet ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
WO-2025121315-A1 CELLULOSE POWDER AND MOLDED BODY 旭化成株式会社 2025-06-12 WO disclosed
WO-2025105451-A1 SOLID PREPARATION 第一三共ヘルスケア株式会社 2025-05-22 WO disclosed
EP-0631782-B1 Stabilized solid pharmaceutical preparation containing dextromethorphan, phenylpropanolamine and caffeine TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-05-06 EP disclosed
US-5726180-A CAFFEINE, DEXTROMETHORPHAN, PHENYLPROPANOLAMINE, IBUPROFEN TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed
US-5629316-A Stabilized solid pharmaceutical preparation and method of producing the same TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-13 US disclosed
EP-0631782-A1 Stabilized solid pharmaceutical preparation containing dextromethorphan, phenylpropanolamine and caffeine Takeda Chemical Industries, Ltd. (JP) 1995-01-04 EP disclosed
JP-H05139996-A COMPOSITION FOR ANTITUSSIVE EXPECTORANT REDUCED IN ITS BITTER TASTE LION CORP 1993-06-08 JP disclosed
JP-S6272688-A TIPEPIDINE CITRATE-CONTAINING COMPOSITION SS PHARMACEUT CO LTD 1987-04-03 JP disclosed
JP-S06272688-A 0001-01-01 JP disclosed