Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048801 | 0.78 | SIGMAR1 (0.41) | POLBSIGMAR1 | |
| SCHEMBL9755772 | 0.73 | SLC6A3 (0.42) | POLBSIGMAR1TDP1MEN1KMT2A | |
| Formamide SCHEMBL28854308 | 0.72 | SIGMAR1 (0.36) | SIGMAR1GAA | |
| SCHEMBL25379874 | 0.71 | LMNA (0.41) | POLBSIGMAR1GAAKDM4E | |
| SCHEMBL8804597 | 0.71 | SIGMAR1 (0.39) | POLBSIGMAR1KDM4E | |
| SCHEMBL10619250 | 0.71 | SIGMAR1 (0.36) | SIGMAR1MEN1KMT2AGAAKDM4E | |
| SCHEMBL24609402 | 0.71 | CYP11B1 (0.40) | CYP11B1CYP11B2POLBSIGMAR1CCR3 | |
| Bromide SCHEMBL29099282 | 0.70 | SIGMAR1 (0.38) | POLBSIGMAR1TDP1KMT2A | |
| SCHEMBL28790693 | 0.70 | ALDH1A1 (0.41) | SIGMAR1MEN1KMT2AGAA | |
| Bromide SCHEMBL28711468 | 0.69 | SIGMAR1 (0.37) | CYP11B1CYP11B2SIGMAR1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207508-A | 9H-pyrrolo-bipyridine derivatives | UCB生物制药私人有限公司 | 2017-09-26 | — | — | CN | disclosed |