Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141629 | 0.89 | TAAR1 (0.40) | TAAR1AOC3TRPA1RIPK1 | |
| SCHEMBL18811511 | 0.87 | SMN1; SMN2 (0.41) | TAAR1AOC3TRPA1RIPK1LMNA | |
| SCHEMBL28850694 | 0.85 | ADRB2 (0.43) | ADRA2ACYP2D6LMNAHIF1AKDM4E | |
| SCHEMBL780943 | 0.76 | TAAR1 (0.39) | TAAR1AOC3TRPA1RIPK1ADRA2A | |
| SCHEMBL2530002 | 0.74 | DPP4 (0.39) | TAAR1CYP2D6LMNADPP4 | |
| SCHEMBL28435238 | 0.73 | TRPA1 (0.52) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL24849720 | 0.72 | TAAR1 (0.36) | TAAR1AOC3TRPA1RIPK1 | |
| SCHEMBL68908 | 0.72 | TSHR (0.38) | TAAR1AOC3TRPA1RIPK1CYP2D6 | |
| SCHEMBL11050400 | 0.72 | ADRA2C (0.44) | TAAR1AOC3TRPA1ADRA2AADRA2C | |
| SCHEMBL8384502 | 0.72 | TAAR1 (0.41) | TAAR1ADRA2AADRA2CCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107235995-B | Chiral dihydrosilane compound and synthesis method and application thereof | 浙江大学 | 2019-12-24 | — | — | CN | disclosed |
| CN-107235995-A | A kind of chiral two silane compound and its synthetic method and application | 浙江大学 | 2017-10-10 | — | — | CN | disclosed |