SCHEMBL281799

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL281930	0.96	DRD2 (0.33)	P4HBCHRM5DRD2ADRB2CHRM2
	SCHEMBL3330517	0.94	P4HB (0.36)	P4HBSCN9A
	SCHEMBL2304018	0.90	USP9X (0.35)	P4HBSCN9A
	SCHEMBL3330531	0.90	P4HB (0.36)	P4HBCHRM5DRD2ADRB2CHRM2
	SCHEMBL3329500	0.89	P4HB (0.35)	P4HBCHRM5DRD2ADRB2CHRM2
	SCHEMBL3328577	0.89	P4HB (0.35)	P4HBCHRM5DRD2ADRB2CHRM2
	SCHEMBL2305458	0.89	P4HB (0.40)	P4HBNPC1RAB9ASCN9A
	SCHEMBL3327533	0.87	P4HB (0.41)	P4HBNPC1RAB9ASCN9ACASP3
	SCHEMBL3330877	0.86	FABP4 (0.36)	P4HBCHRM5DRD2ADRB2CHRM2
	SCHEMBL2307348	0.85	FABP4 (0.37)	P4HBCHRM5DRD2ADRB2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.