Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2821800 | 0.99 | HSD11B1 (0.35) | HSD11B1CHRNB4CHRNA3TP53HCRTR1 | |
| SCHEMBL2846380 | 0.86 | IL4I1 (0.38) | HSD11B1CHRNB4CHRNA3TP53MAOB | |
| SCHEMBL668390 | 0.85 | ACHE (0.36) | TP53NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2822574 | 0.85 | IL4I1 (0.37) | HSD11B1CHRNB4CHRNA3TP53MAOB | |
| SCHEMBL2820263 | 0.79 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL2823335 | 0.78 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2822113 | 0.77 | ALDH1A1 (0.43) | TP53NPC1RAB9A | |
| SCHEMBL13089333 | 0.76 | CYP1A2 (0.37) | — | |
| Hydrochloric Acid SCHEMBL2822814 | 0.76 | ALDH1A1 (0.42) | TP53NPC1RAB9A | |
| SCHEMBL2821301 | 0.76 | CHRNA7 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922320-B1 | DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2010-10-27 | — | — | EP | claimed |