Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2A | Q92830 | 4/20 | 0.58 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 4/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248284 | 0.85 | CASP3 (0.59) | KAT2AKAT2BCASP3FAAHMGLL | |
| SCHEMBL8356352 | 0.82 | CASP3 (0.56) | KAT2AKAT2BCASP3FAAHMGLL | |
| SCHEMBL20022714 | 0.82 | CASP3 (0.63) | KAT2AKAT2BCASP3FAAHMGLL | |
| SCHEMBL11278746 | 0.79 | CASP3 (0.74) | KAT2AKAT2BCASP3FAAHMGLL | |
| SCHEMBL12179299 | 0.77 | CASP3 (0.65) | KAT2AKAT2BCASP3 | |
| SCHEMBL358740 | 0.77 | FAAH (0.77) | KAT2AKAT2BCASP3FAAHMGLL | |
| SCHEMBL8356552 | 0.77 | CASP3 (0.66) | KAT2AKAT2BCASP3FAAHMGLL | |
| SCHEMBL24836229 | 0.76 | FAAH (0.76) | KAT2AKAT2BCASP3FAAHMGLL | |
| SCHEMBL24836231 | 0.76 | FAAH (0.81) | KAT2AKAT2BCASP3FAAHMGLL | |
| SCHEMBL765778 | 0.76 | FAAH (0.57) | KAT2AKAT2BCASP3FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107690429-A | composition for the treatment and/or prevention of cell or tissue necrosis, specifically targeting cathepsin C and/or CE L a1 and/or CE L A3A and/or enzymes structurally related thereto | ELA制药有限公司 | 2018-02-13 | — | — | CN | disclosed |