Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613090 | 0.86 | TGM2 (0.65) | TGM2PTPN1PTPN11BTKF13A1 | |
| SCHEMBL31228347 | 0.86 | TGM2 (0.65) | TGM2PTPN1PTPN11BTKF13A1 | |
| SCHEMBL2092372 | 0.79 | SIGMAR1 (0.47) | LMNASIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9357321 | 0.78 | TGM2 (0.57) | TGM2PTPN1PTPN11BTKF13A1 | |
| SCHEMBL29366956 | 0.78 | MMP1 (0.59) | TGM2PTPN1PTPN11LMNAKDM4E | |
| SCHEMBL17443378 | 0.78 | TGM2 (0.57) | TGM2PTPN1PTPN11BTKF13A1 | |
| SCHEMBL413017 | 0.78 | MMP1 (0.59) | TGM2PTPN1PTPN11LMNAKDM4E | |
| SCHEMBL2761954 | 0.78 | TGM2 (0.62) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL505134 | 0.78 | HPGD (0.58) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL505135 | 0.78 | HPGD (0.58) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028569-B | Indoline-2-ketone-3-acetamide series compound and preparation method thereof | 浙大城市学院 | 2023-12-22 | — | — | CN | claimed |
| CN-114394925-A | Preparation method of polysubstituted indolone derivatives | 广东医科大学 | 2022-04-26 | — | — | CN | claimed |
| CN-114105775-A | Preparation method of substituted iodobenzene with terminal double bond | 武汉工程大学 | 2022-03-01 | — | — | CN | claimed |
| EP-4673482-A1 | RADIOPAQUE CROSSLINKED ACRYLAMIDE COPOLYMERS AND USES THEREOF | Boston Scientific Scimed Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| CN-119954783-A | Heterocyclically substituted gamma, delta-unsaturated butenolide and use thereof | 遵义医科大学 | 2025-05-09 | — | — | CN | disclosed |
| WO-2024182584-A1 | RADIOPAQUE CROSSLINKED ACRYLAMIDE COPOLYMERS AND USES THEREOF | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| US-20240293583-A1 | RADIOPAQUE CROSSLINKED ACRYLAMIDE COPOLYMERS AND USES THEREOF | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2024-09-05 | — | — | US | disclosed |
| CN-114394925-A | Preparation method of polysubstituted indolone derivatives | 广东医科大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-114394925-A | Preparation method of polysubstituted indolone derivatives | 广东医科大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-114105775-A | Preparation method of substituted iodobenzene with terminal double bond | 武汉工程大学 | 2022-03-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293583-A1 | RADIOPAQUE CROSSLINKED ACRYLAMIDE COPOLYMERS AND USES THEREOF | RAD51, TSG101, BRCA1 | TGM2 1994/4885PTPN1 209/4885PTPN11 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.