Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 3/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321744 | 0.81 | PDE10A (0.40) | WNT3AKCNH2PDE10AMAP4K4PIK3CA | |
| SCHEMBL30527142 | 0.79 | CYP2A6 (0.50) | TRPV4 | |
| SCHEMBL17247906 | 0.79 | CYP2A6 (0.50) | TRPV4 | |
| SCHEMBL13750578 | 0.75 | WNT3A (0.47) | WNT3APDE10A | |
| SCHEMBL28209158 | 0.75 | KIF11 (0.50) | — | |
| SCHEMBL1723870 | 0.74 | MAP4K4 (0.44) | WNT3AMAP4K4 | |
| SCHEMBL17619985 | 0.74 | TRPV4 (0.47) | TRPV4WNT3ATRPV3KCNH2MAP4K4 | |
| SCHEMBL30636554 | 0.74 | CYP2A6 (0.56) | TRPV4 | |
| SCHEMBL16835948 | 0.73 | KCNH2 (0.46) | TRPV4TRPV3KCNH2MAP4K4PIK3CA | |
| SCHEMBL20427626 | 0.72 | HPGDS (0.50) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061974-B | Maleimide derivatives as the conditioning agent of WNT approach | 新加坡科技研究局 | 2018-04-20 | — | — | CN | disclosed |