Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.61 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3337224 | 0.78 | NUDT1 (0.61) | ACHEAPPKDM4EKDM1ALMNA | |
| SCHEMBL4593685 | 0.77 | NPY5R (0.67) | ADORA3ACHEAPPKDM4EKMT2A | |
| SCHEMBL31060818 | 0.76 | ADORA3 (1.00) | ADORA3ACHEAPPKDM4EKMT2A | |
| SCHEMBL3074031 | 0.74 | KDM4E (0.71) | ADORA3ACHEAPPKDM4EKMT2A | |
| SCHEMBL5022019 | 0.74 | ADORA1 (0.55) | ADORA3ADORA1KDM4EKMT2AMAPT | |
| SCHEMBL13975527 | 0.74 | ALOX15 (0.45) | ADORA3ACHEAPPKDM4EMAPT | |
| SCHEMBL28274202 | 0.73 | MAOA (0.42) | APPKDM4EKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL823647 | 0.73 | L3MBTL1 (0.41) | ADORA3ACHEAPPADORA1KDM4E | |
| Bicarbonate SCHEMBL11023181 | 0.72 | MAOA (0.48) | APPKDM4EKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11561386 | 0.71 | L3MBTL1 (0.51) | ADORA3ADORA1KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108014114-A | Chloro acetylamino quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | claimed |
| CN-108084162-B | Dimethoxy benzene aminoacetylamino benzo [d] azepine * base quinazoline compounds and preparation and application | 浙江工业大学 | 2019-11-29 | — | — | CN | disclosed |
| CN-108033949-B | 6- (2- dipropyl aminoacetylamino) quinazoline compounds and preparation and application | 浙江工业大学 | 2019-11-29 | — | — | CN | disclosed |
| CN-108324719-A | Adjacent toluidino acetylamino anisyl benzo-aza * bases quinazoline compounds are preparing the application in treating uterine neck cancer drug | 浙江工业大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-108245521-A | Dipropyl aminoacetylamino benzo-aza * bases quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-108250185-A | 6- (2- (adjacent toluidino) acetylamino) quinazoline compounds and preparation and application | 浙江工业大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-108125961-A | Morpholinyl acetylamino anisyl benzo-aza * bases quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108125958-A | Adjacent toluidino acetylamino chloro benzo azepine * bases quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108125959-A | Dimethoxy benzene aminoacetylamino quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108084162-A | Dimethoxy benzene aminoacetylamino benzo [d] azepine * bases quinazoline compounds and preparation and application | 浙江工业大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-108078994-A | 6- (2- morpholinyls acetylamino) quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-108042546-A | Morpholinyl acetylamino benzo [d] azepine * bases quinazoline compounds are preparing the application in treating uterine neck cancer drug | 浙江工业大学 | 2018-05-18 | — | — | CN | disclosed |
| CN-108033949-A | 6- (2- dipropyls aminoacetylamino) quinazoline compounds and preparation and application | 浙江工业大学 | 2018-05-15 | — | — | CN | disclosed |
| CN-108017621-A | Morpholinyl acetylamino dimethoxy benzo [d] azepine * bases quinazoline compounds and preparation and application | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108014112-A | Adjacent toluidino acetylamino benzo [d] azepine * bases quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108014114-A | Chloro acetylamino quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108014114-A | Chloro acetylamino quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-108014114-A | Chloro acetylamino quinazoline compounds are preparing the application in treating lung-cancer medicament | 浙江工业大学 | 2018-05-11 | — | — | CN | disclosed |