Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | STAMBP | O95630 | 1/20 | 0.52 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124745 | 0.84 | NAMPT (0.60) | RAB9ANPC1PSMD14STAMBPCOPS5 | |
| SCHEMBL2712690 | 0.81 | GAA (0.55) | LMNASMN1; SMN2RAB9APSMD14STAMBP | |
| SCHEMBL22983004 | 0.78 | RAB9A (0.61) | LMNAHIF1AROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL12614021 | 0.78 | LMNA (0.56) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL3647333 | 0.77 | PSMD14 (0.53) | LMNAROCK1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6643666 | 0.76 | LMNA (0.67) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL31678616 | 0.75 | THRB (0.57) | ROCK2HDAC1HDAC6SMN1; SMN2RAB9A | |
| SCHEMBL11591966 | 0.74 | LMNA (0.69) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL1571386 | 0.74 | LMNA (1.00) | LMNAHIF1AROCK2ROCK1RAB9A | |
| SCHEMBL13639895 | 0.73 | KDM4E (0.67) | LMNASMN1; SMN2RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024211969-A1 | PPARG MODULATORS | Setonix Pharmaceuticals Pty Ltd (AU) | 2024-10-17 | — | — | WO | disclosed |
| CN-108299418-A | A kind of synthetic method of the thiazolyl nicotinamide compound of antiallergy and asthma | 刘双伟 | 2018-07-20 | — | — | CN | disclosed |