Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | AQP4 | P55087 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17079639 | 0.83 | CSNK2A2 (0.53) | LMNARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL28232648 | 0.78 | LMNA (0.58) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL13639895 | 0.75 | KDM4E (0.67) | LMNARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL11591966 | 0.73 | LMNA (0.69) | LMNAHIF1AROCK2ROCK1AQP4 | |
| SCHEMBL1571386 | 0.73 | LMNA (1.00) | LMNAHIF1AROCK2ROCK1RAB9A | |
| SCHEMBL8162429 | 0.72 | HDAC1 (0.69) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL5361880 | 0.71 | HDAC1 (0.74) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL2000041 | 0.71 | HDAC1 (0.74) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| Nicotinanilide SCHEMBL352439 | 0.71 | LMNA (0.83) | LMNAHIF1AROCK2ROCK1RAB9A | |
| SCHEMBL14880208 | 0.71 | ROCK2 (1.00) | LMNAHIF1AROCK2ROCK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9370184-B2 | 6-pyridone-2-carbamoyl-azoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2016-06-21 | — | — | US | disclosed |
| EP-2688885-B1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER IP GMBH (DE) | 2016-06-01 | — | — | EP | disclosed |
| EP-2844650-B1 | 6-PYRIDON-2-CARBAMOYL-AZOLES AND THEIR APPLICATION AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2016-03-23 | — | — | EP | disclosed |
| US-9101141-B2 | N-(1,3,4-oxadiazol-2-yl)arylcarboxamides and use thereof as herbicides | BAYER INTERLLECTUAL PROPERTY GMBH (DE) | 2015-08-11 | — | — | US | disclosed |
| US-20150111747-A1 | 6-PYRIDONE-2-CARBAMOYL-AZOLES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | US | disclosed |
| US-20140080705-A1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| EP-2688885-A1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2014-01-29 | — | — | EP | disclosed |
| WO-2012126932-A1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080705-A1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES | PRDX4, CBR3, AOX1 | LMNA 3484/4885HIF1A 1626/4885ROCK2 1923/4885 |
| US-20150111747-A1 | 6-PYRIDONE-2-CARBAMOYL-AZOLES AND THEIR USE AS HERBICIDES | PDXK, PNPO, PRDX6 | LMNA 3962/4885HIF1A 3730/4885ROCK2 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.