Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802029 | 0.80 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL27377077 | 0.80 | KEAP1 (0.34) | TRPV4DRD2SIGMAR1 | |
| SCHEMBL20688772 | 0.80 | CTSD (0.44) | CTSDCTSLCTSBCTSS | |
| SCHEMBL22181631 | 0.79 | ALOX15 (0.35) | DRD2 | |
| SCHEMBL22181259 | 0.79 | METAP2 (0.35) | TRPV4METAP2DRD2AAK1SIGMAR1 | |
| SCHEMBL22181464 | 0.77 | NR1H2 (0.36) | DRD2 | |
| SCHEMBL31250574 | 0.76 | SIGMAR1 (0.44) | DRD2SIGMAR1 | |
| SCHEMBL22181206 | 0.76 | ACHE (0.37) | DRD2HTR2CSLC6A4 | |
| SCHEMBL22181263 | 0.76 | CCR5 (0.35) | TRPV4DRD2 | |
| SCHEMBL25977462 | 0.76 | SIGMAR1 (0.50) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779123-A | Fused tetracyclic compound, its composition and purposes | 泰博生物科技有限公司 | 2018-11-09 | — | — | CN | disclosed |