Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pantothenic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | VNN1 | O95497 | 13/20 | 0.53 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pantothenic Acid SCHEMBL27903325 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL124921 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL29390839 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL124920 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL10774482 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL27833354 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL11750103 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1ZDHHC20BBOX1 | |
| Pantothenic Acid SCHEMBL27833355 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL11750098 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1ZDHHC20BBOX1 | |
| Pantothenic Acid SCHEMBL27833357 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109280015-A | A kind of synthesis of D-VB5 sodium and chiral separation method | 无锡凯夫制药有限公司 | 2019-01-29 | — | — | CN | disclosed |