SCHEMBL2829025

SCHEMBL2829025

Oc1ccccc1-n1nccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.48
GAA P10253 3/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 4/20 0.42
HPGD P15428 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
POLB P06746 4/20 0.42
KDM4E B2RXH2 4/20 0.42
MAPT P10636 3/20 0.42
XBP1 P17861 1/20 0.42
MAPK1 P28482 1/20 0.42
KCNMA1 Q12791 1/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
LMNA P02545 3/20 0.41
CA12 O43570 1/20 0.41
GMNN O75496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30686694 1.00 IDO1 (0.48) IDO1GAAHTTALDH1A1HPGD
SCHEMBL1128641 0.76 KCNMA1 (0.42) IDO1GAAHTTALDH1A1HPGD
SCHEMBL59309 0.74 RAB9A (0.61) IDO1GAAHTTALDH1A1HPGD
SCHEMBL29363181 0.74 RAB9A (0.61) IDO1GAAHTTALDH1A1HPGD
SCHEMBL31621955 0.74 CA12 (0.55) KDM4ERAB9ACA12CA2ALOX15
SCHEMBL16141036 0.73 ALDH1A1 (0.53) IDO1GAAHTTALDH1A1HPGD
Methane SCHEMBL10729260 0.73 RAB9A (0.59) IDO1GAAHTTALDH1A1HPGD
SCHEMBL4461012 0.71 GAA (0.48) GAAHTTALDH1A1HPGDPOLB
SCHEMBL4550926 0.71 FLT3 (0.44) ALDH1A1HPGDHSD17B10KDM4EMAPT
SCHEMBL17145963 0.71 MGLL (0.43) ALDH1A1HPGDKDM4ERAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108842932-B High-adhesion polyolefin anti-adhesion film and preparation method thereof 江苏优珀斯材料科技有限公司 2021-03-19 CN claimed
CN-115279387-A Topical composition comprising arillus longan combined crude drug extract for inhibiting TSLP and treating or improving skin inflammation diseases, and its application (株)美迪合伙来音 2022-11-01 CN disclosed
CN-108842932-B High-adhesion polyolefin anti-adhesion film and preparation method thereof 江苏优珀斯材料科技有限公司 2021-03-19 CN disclosed
US-20170275534-A1 ULTRAVIOLET LIGHT ABSORBERS TRANSITIONS OPTICAL, INC. 2017-09-28 US disclosed
US-8697503-B2 Active matrix displays and other electronic devices having plastic substrates KONINKLIJKE PHILIPS N.V. (NL) 2014-04-15 US disclosed
CN-103219285-A Active matrix displays and other electronic devices having plastic substrates KONINKL PHILIPS ELECTRONICS NV 2013-07-24 CN disclosed
US-20100163878-A1 ACTIVE MATRIX DISPLAYS AND OTHER ELECTRONIC DEVICES HAVING PLASTIC SUBSTRATES KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-07-01 US disclosed
CN-101501832-A Active matrix displays and other electronic devices with plastic substrates KONINKL PHILIPS ELECTRONICS NV (NL) 2009-08-05 CN disclosed
EP-2052406-A2 ACTIVE MATRIX DISPLAYS AND OTHER ELECTRONIC DEVICES HAVING PLASTIC SUBSTRATES Koninklijke Philips Electronics N.V. (NL) 2009-04-29 EP disclosed
US-20090036555-A1 Stabilization of iodine biocides LANXESS DEUTSCHLAND GMBH (DE) 2009-02-05 US disclosed
WO-2008018026-A2 ACTIVE MATRIX DISPLAYS AND OTHER ELECTRONIC DEVICES HAVING PLASTIC SUBSTRATES KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-02-14 WO disclosed
CN-1925833-A Keratin dyeing compounds, keratin dyeing compositions containing them, and their use PROCTER & GAMBLE (US) 2007-03-07 CN disclosed
US-4472546-A BLENDS WITH A2-(O-HYDROXYPHENYL)BENZOTRIAZOLE, 2-HYDROXYBENZOPHENONE, ORGANIC PHOSPHITE AND HINDERED PHENOL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1984-09-18 US disclosed
EP-0099231-A2 Polyphenylene ether resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1984-01-25 EP disclosed
US-3880875-A Ultraviolet absorbing 2-(2-hydroxyphenyl) 2H-1,2,3-triazole derivatives STROBEL ALBERT F 1975-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036555-A1 Stabilization of iodine biocides LCT, BTD, HDHD5 IDO1 658/4885GAA 1460/4885HTT 36/4885
US-20170275534-A1 ULTRAVIOLET LIGHT ABSORBERS MCM4, ERCC1, ERCC4 IDO1 158/4885GAA 1610/4885HTT 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.