Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR5A | P47898 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872613 | 0.90 | HTR1A (0.47) | HTR1AHTR7HTR6HTR1BHTR2C | |
| SCHEMBL28687269 | 0.88 | SPR (0.40) | PLGPLAUSPRHTR1AHTR1B | |
| SCHEMBL27785494 | 0.81 | HTR2C (0.40) | SPRHTR1AHTR1BHTR2CCYP1A2 | |
| SCHEMBL28043663 | 0.81 | IMPDH2 (0.38) | PLGPLAUHTR2CMEN1KMT2A | |
| SCHEMBL27526971 | 0.80 | NR4A2 (0.44) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL27528319 | 0.79 | CYP2A6 (0.51) | KDM4EALDH1A1IMPDH2 | |
| SCHEMBL27550865 | 0.79 | NR4A2 (0.46) | SPRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28658779 | 0.79 | GPR84 (0.43) | HTR1AHTR2C | |
| SCHEMBL27552422 | 0.79 | ALDH1A1 (0.35) | HTR2CCYP1A2KDM4EALDH1A1 | |
| SCHEMBL28819111 | 0.78 | HTR1A (0.47) | HTR1AHTR1BHTR2CHTR1DHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-A | A kind of synthetic method of 2- substituted indole derivative | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |