Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL11281416 | 0.96 | F2 (0.45) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL11121502 | 0.96 | F2 (0.45) | F2PRSS1PRSS2PRSS3CA1 | |
| Tetraphenylphosphonium SCHEMBL6905021 | 0.87 | F2 (0.42) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL29435078 | 0.82 | ALOX15 (0.48) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL347237 | 0.82 | ALOX15 (0.48) | F2PRSS1PRSS2PRSS3CA1 | |
| Potassium Ion SCHEMBL11554750 | 0.82 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL6903429 | 0.81 | CA12 (0.45) | F2PRSS1PRSS2PRSS3ALOX15 | |
| SCHEMBL60211 | 0.81 | ALOX15 (0.47) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL30842657 | 0.81 | ALOX15 (0.47) | F2PRSS1PRSS2PRSS3CA1 | |
| Ammonia Solution, Strong SCHEMBL5169579 | 0.79 | ALOX15 (0.46) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754196-B2 | Cosmetic composition comprising fiber | L'OREAL (FR) | 2010-07-13 | — | — | US | disclosed |
| US-20040096473-A1 | Cosmetic composition comprising fibres | L'OREAL (FR) | 2004-05-20 | — | — | US | disclosed |
| US-5530093-A | SOIL RELEASE AGENTS, ANTISTATIC AGENTS FOR TEXTILE FINISHING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096473-A1 | Cosmetic composition comprising fibres | KRT18, CUTA, SMC3 | F2 539/4885PRSS1 3453/4885PRSS2 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.