Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724110 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL29724092 | 0.86 | MAPT (0.48) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL28668402 | 0.86 | MAPT (0.48) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL8487393 | 0.82 | NOTUM (0.34) | ALDH1A1MAPTLMNAHPGDTSHR | |
| SCHEMBL8488373 | 0.79 | GPR174 (0.58) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL29353417 | 0.78 | LMNA (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL9687137 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL28678768 | 0.78 | LMNA (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL28697213 | 0.78 | MAPT (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL29724074 | 0.77 | TOP2A (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113788828-B | Preparation method and application of isofraxine analogue from norfloxacin to isofraxine analogue | 黄河水利职业技术学院 | 2023-06-30 | — | — | CN | disclosed |
| CN-109776411-B | Nitrogen mustard carbostyril derivative and preparation method and application thereof | 石家庄学院 | 2022-06-07 | — | — | CN | disclosed |
| CN-113788828-A | Isoleucinine analogue, preparation method and application of isoleucinine analogue from norfloxacin to isoleucinine analogue | 黄河水利职业技术学院 | 2021-12-14 | — | — | CN | disclosed |
| CN-109776411-A | Mustargen Carbostyril derivative and its preparation method and application | 石家庄学院 | 2019-05-21 | — | — | CN | disclosed |