Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | BRS3 | P32247 | 5/20 | 0.43 |
| ▸ | SCN1A | P35498 | 3/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854183 | 0.89 | ACHE (0.48) | SLC6A3ACHESLC6A4BRS3SCN1A | |
| SCHEMBL8875151 | 0.88 | ACHE (0.48) | SLC6A3ACHESLC6A4BRS3SCN1A | |
| SCHEMBL489306 | 0.86 | NR1H2 (0.48) | SLC6A3ACHESLC6A4BRS3SCN1A | |
| SCHEMBL4074654 | 0.85 | ALDH1A1 (0.47) | SLC6A3ACHESLC6A4BRS3LTB4R2 | |
| SCHEMBL18280658 | 0.85 | CYP4F2 (0.45) | SLC6A3ACHESLC6A4SCN1ASCN2A | |
| SCHEMBL29390423 | 0.84 | SLC6A3 (0.68) | SLC6A3SLC6A4BRS3SLC6A2LTB4R2 | |
| SCHEMBL6900241 | 0.84 | SLC6A3 (0.68) | SLC6A3ACHESLC6A4BRS3SCN1A | |
| SCHEMBL562 | 0.84 | SLC6A3 (0.68) | SLC6A3SLC6A4BRS3SLC6A2LTB4R2 | |
| SCHEMBL1069726 | 0.83 | FOLH1 (0.47) | ACHESCN1ASCN2ASCN3ALTB4R2 | |
| SCHEMBL9447390 | 0.83 | ACHE (0.46) | SLC6A3ACHESLC6A4BRS3SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008356-B | Preparation method of telmisartan | 浙江华海药业股份有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-115108906-A | Novel method for preparing 4 '-bromomethyl- [1,1' -biphenyl ] -2-tert-butyl formate | 临海市华南化工有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-110156761-B | Compound containing coumarin-biphenyl skeleton, preparation method and application thereof | 郑州大学 | 2022-08-09 | — | — | CN | claimed |
| CN-113200934-B | Compound containing benzomorpholone-biphenyl skeleton and preparation method and application thereof | 郑州大学 | 2022-05-31 | — | — | CN | claimed |
| CN-113200934-A | Compound containing benzomorpholone-biphenyl skeleton and preparation method and application thereof | 郑州大学 | 2021-08-03 | — | — | CN | claimed |
| CN-110156761-A | Containing cumarin-biphenyl backbone compound, preparation method and applications | 郑州大学 | 2019-08-23 | — | — | CN | claimed |
| US-20060167301-A1 | Process for producing an aralkyl compound, a dehalogenation method of an aralkyl halide compound and a method for recovering an aralkyl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-07-27 | — | — | US | claimed |
| EP-1683777-A1 | A process for producing an aralkyl compound, a dehalogenation method of an aralkyl halide compound and a method for recovering an aralkyl compound | Sumitomo Chemical Company, Limited (JP) | 2006-07-26 | — | — | EP | claimed |
| EP-0389153-B1 | Anti-stick layer for thermal printing | MINNESOTA MINING & MFG (US) | 1997-05-14 | — | — | EP | claimed |
| JP-3148266-A | — | — | None | — | — | JP | disclosed |
| WO-2025011553-A1 | AZOLE COMPOUNDS, SYNTHESIS THEREFOR AND PHARMACEUTICAL USE THEREOF | 四川农业大学 | 2025-01-16 | — | — | WO | disclosed |
| CN-115215823-B | FXR modulator, preparation method, pharmaceutical composition and application thereof | 北京百思致道管理顾问中心(有限合伙) | 2024-07-26 | — | — | CN | disclosed |
| US-20240239775-A1 | FXR REGULATOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | BEIJING BEST PATHWAY MANAGEMENT CONSULTING CENTER (LIMITED PARTNERSHIP) (CN) | 2024-07-18 | — | — | US | disclosed |
| EP-4324825-A1 | FXR REGULATOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Beijing Best Pathway Management Consulting Center (Limited Partnership) (CN) | 2024-02-21 | — | — | EP | disclosed |
| EP-0400974-A2 | Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0400835-A1 | Substituted benzimidazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0324377-A2 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |
| EP-0323841-A2 | Substituted pyrrole, pyrazole and triazole angiotensin II antagonists | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-12 | — | — | EP | disclosed |
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239775-A1 | FXR REGULATOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | SLC10A1, NR1H4, FXR1 | SLC6A3 1962/4885ACHE 4566/4885SLC6A4 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.