SCHEMBL877342

SCHEMBL877342

COc1ccccc1C(=O)NS(=O)(=O)c1ccc(C(I)NC(N)=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.49
FLT1 P17948 4/20 0.47
FLT4 P35916 4/20 0.47
KDR P35968 4/20 0.47
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
CTSD P07339 1/20 0.45
POLB P06746 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
KAT6A Q92794 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
THRB P10828 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
RAB9A P51151 1/20 0.42
BCL2L1 Q07817 1/20 0.41
MCL1 Q07820 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15495162 0.80 RXFP1 (0.60) GAAFLT1FLT4KDRALDH1A1
SCHEMBL18803129 0.80 POLB (0.64) GAAFLT1FLT4KDRCTSD
Formamide SCHEMBL28301130 0.80 FLT1 (0.52) GAAFLT1FLT4KDRALDH1A1
SCHEMBL7797528 0.80 GAA (0.59) GAAFLT1FLT4KDRALDH1A1
SCHEMBL9414560 0.79 POLB (0.68) GAAFLT1FLT4KDRCTSD
SCHEMBL16244081 0.79 KDM4E (0.62) GAAFLT1FLT4KDRALDH1A1
SCHEMBL5402610 0.78 GAA (0.52) GAAFLT1FLT4KDRALDH1A1
SCHEMBL125423 0.78 L3MBTL1 (0.54) GAAFLT1FLT4KDRALDH1A1
SCHEMBL871964 0.77 HPGD (0.57) GAAFLT1FLT4KDRALDH1A1
SCHEMBL16634981 0.76 GAA (0.57) GAAFLT1FLT4KDRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012038476-A1 USE OF ACTIVE INGREDIENTS FOR CONTROLLING NEMATODES IN NEMATODE-RESISTANT CROPS BAYER CROPSCIENCE AG (DE) 2012-03-29 WO disclosed