Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MGMT | P16455 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306200 | 0.86 | GLP1R (0.33) | MAPTTDP1KDM4EMAPK1LMNA | |
| SCHEMBL28307340 | 0.83 | MAPT (0.39) | MAPTTDP1ATMALDH1A1LMNA | |
| SCHEMBL28307341 | 0.76 | HTT (0.45) | MAPTTDP1ATMALDH1A1LMNA | |
| SCHEMBL28306176 | 0.75 | KMT2A (0.37) | MAPTTDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL28307339 | 0.72 | MAPT (0.38) | MAPTTDP1MAPK1ATMALDH1A1 | |
| SCHEMBL28307335 | 0.72 | HTT (0.38) | MAPTTDP1KDM4EALDH1A1LMNA | |
| SCHEMBL28307334 | 0.70 | TLR8 (0.37) | MAPTTDP1ALDH1A1LMNAPOLB | |
| SCHEMBL28306205 | 0.67 | KMT2A (0.35) | MAPTMAPK1ATMALDH1A1LMNA | |
| SCHEMBL28306175 | 0.65 | MAPT (0.43) | MAPTTDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL28946160 | 0.62 | MAPT (0.39) | MAPTALDH1A1LMNAGLP1RHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |