SCHEMBL28308673

SCHEMBL28308673

C=CCOc1c(CC=C)ccc2cc(CC=C)ccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
PPARG P37231 2/20 0.37
PPARD Q03181 2/20 0.37
PPARA Q07869 1/20 0.37
XDH P47989 1/20 0.37
MAPT P10636 4/20 0.36
CYP3A4 P08684 3/20 0.36
CYP1A2 P05177 1/20 0.36
GABRA1 P14867 7/20 0.36
GABRB2 P47870 7/20 0.36
CNR2 P34972 6/20 0.36
ALOX5 P09917 4/20 0.36
MEN1 O00255 3/20 0.36
GAA P10253 3/20 0.36
KMT2A Q03164 3/20 0.36
CNR1 P21554 3/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH2 P05091 1/20 0.36
AKR1B1 P15121 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21840790 0.82 TLR4 (0.36) ALDH1A1MAPTCYP3A4GABRA1GABRB2
SCHEMBL28540281 0.80 HPGD (0.47) ALDH1A1MAPTGAAHPGDPOLB
SCHEMBL1059702 0.78 ALOX5 (0.51) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL28309526 0.75 ALDH1A1 (0.32) ALDH1A1MAPTHPGDCA12CA1
SCHEMBL9253029 0.73 ALDH1A1 (0.36) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL3220497 0.71 XDH (0.43) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL11586876 0.71 CNR2 (0.52) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL3259762 0.71 XDH (0.58) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL11602955 0.70 GABRA1 (0.47) ALDH1A1MAPTGABRA1GABRB2KDM4E
SCHEMBL8626516 0.70 CYP3A4 (0.39) ALDH1A1PPARGPPARDPPARAXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110088164-A Composition epoxy resin DIC株式会社 2019-08-02 CN disclosed