Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | IL33 | O95760 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539833 | 0.90 | SIGMAR1 (0.58) | OPRK1OPRM1SIGMAR1HRH2KDM4E | |
| SCHEMBL8543954 | 0.85 | KDM4E (0.64) | OPRK1OPRM1SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL22201130 | 0.85 | CHRNB2 (0.53) | OPRK1OPRM1KDM4EALDH1A1 | |
| SCHEMBL2172790 | 0.85 | CHRNB2 (0.53) | OPRK1OPRM1KDM4EALDH1A1 | |
| SCHEMBL11382546 | 0.83 | POLB (0.55) | OPRK1 | |
| SCHEMBL23064641 | 0.82 | DRD2 (0.54) | OPRK1OPRM1SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL2047049 | 0.81 | HTR1A (0.49) | OPRK1OPRM1KDM4EALDH1A1RORC | |
| SCHEMBL23747732 | 0.81 | OPRK1 (0.52) | OPRK1OPRM1SIGMAR1HRH2IL33 | |
| SCHEMBL18862021 | 0.81 | OPRK1 (0.52) | OPRK1OPRM1IL33ALDH1A1MEN1 | |
| SCHEMBL24365232 | 0.81 | KDM4E (0.56) | OPRK1OPRM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066238-A | Fullerene phenylate class pyrrolidines phenylate analog derivative and its preparation method and application | 西南科技大学 | 2019-07-30 | — | — | CN | disclosed |