SCHEMBL28354575

SCHEMBL28354575

CS(=O)(=O)c1ccc(F)c([Ti])c1F

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.34
PTGS2 P35354 10/20 0.33
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12560651 0.80 LMNA (0.44) CCR2L3MBTL1PTGS2LMNAHSD17B10
SCHEMBL27467331 0.80 PSIP1 (0.33) CCR2
SCHEMBL12468302 0.75 CCR2 (0.39) CCR2L3MBTL1PTGS2LMNAHSD17B10
SCHEMBL4596861 0.71 CYP3A4 (0.40) L3MBTL1PTGS2HSD17B10
SCHEMBL4422508 0.71 FABP4 (0.44) CCR2
SCHEMBL6732039 0.70 L3MBTL1 (0.36) CCR2L3MBTL1PTGS2
SCHEMBL26298434 0.70 L3MBTL1 (0.45) CCR2L3MBTL1PTGS2
SCHEMBL775432 0.70 PTGES2 (0.46) CCR2PTGS2
SCHEMBL20226659 0.68 L3MBTL1 (0.44) CCR2L3MBTL1PTGS2LMNAHSD17B10
SCHEMBL14142087 0.68 ENPP2 (0.37) CCR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107709408-B Precursor composition, photosensitive resin composition, method for producing precursor composition, cured film, method for producing cured film, and semiconductor device 富士胶片株式会社 2020-02-14 CN disclosed