Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NGFR | P08138 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27831437 | 0.83 | ALDH1A1 (0.55) | GAABAZ2BALDH1A1KDM4ETHRB | |
| SCHEMBL6631783 | 0.83 | NGFR (0.43) | NGFRGAACA12CA9BAZ2B | |
| SCHEMBL21809222 | 0.80 | KEAP1 (0.50) | GAABAZ2BALDH1A1KDM4ELMNA | |
| SCHEMBL3931733 | 0.79 | KDM4E (0.69) | GAAALDH1A1KDM4ETHRBHPGD | |
| SCHEMBL6188992 | 0.78 | ALDH1A1 (0.41) | NGFRGAACA12CA9PARP1 | |
| SCHEMBL6185980 | 0.78 | LMNA (0.41) | NGFRGAACA12CA9PARP1 | |
| SCHEMBL7344801 | 0.78 | ALDH1A1 (0.67) | GAAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL6634289 | 0.77 | RAB9A (0.53) | GAAHPGDKMT2ALMNARAB9A | |
| SCHEMBL2161332 | 0.76 | L3MBTL1 (0.50) | GAAALDH1A1KDM4ETHRBHPGD | |
| SCHEMBL6191071 | 0.76 | TUBB1 (0.44) | GAACA12CA9ALDH1A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818609-A | Preparation method and application of 3-acetyl indole BRPF1 inhibitor | 中国药科大学 | 2020-02-21 | — | — | CN | disclosed |